Publications
The complexome contextualizes proteomics data to fingerprint biological states and highlight perturbed functional modules in disease
Mainak Guharoy, Isabelle Adant, Matthew Bird, Alexander Botzki, James Collier, Jonas Dehairs, Stefaan Derveaux, Simon Devos, Geert Goeminne, Francis Impens, Andrea Jáñez Pedrayes, Rekin’s Janky, Ruth Maes, Pedro Magalhães, Teresa M. Maia, Wouter Meersseman, Daisy Rymen, Johannes V. Swinnen, Delphi Van Haver, Dries Verdegem, Peter Witters, David Cassiman & Bart Ghesquiere
npj Systems Biology and Applications 2026
A biosynthetic gene cluster for three post-chorismate pathways in Arabidopsis
Meng Peng, Jin Li, Xinyu Liu, Anran Liu, Barbara De Meester, Marlies Brouckaert, Geert Goeminne, Kris Morreel, Yanding Li, Vitaliy I. Timokhin, Ruben Vanholme, John Ralph & Wout Boerjan
Nature Plants 2026
CRISPR/Cas9 editing of p-COUMAROYL-CoA:MONOLIGNOL TRANSFERASE 1 in maize alters phenolic metabolism, lignin structure, and lignin-first biomass processing
Dyoni M. Oliveira, Marina de L.S. Saleme, Rebecca A. Smith, Thijs Vangeel, Marcelo de F. Lima, Alexandra A. Chanoca, Thatiane R. Mota, Yasmine Vanhevel, Griet Coussens, Korneel Van Aelst, Jordi Geerts, Iris Cornet, Dries Vaneechoutte, Klaas Vandepoele, Laurens Pauwels, Geert Goeminne, Kris Morreel, Bert F. Sels, John Ralph, Ruben Vanholme, Wout Boerjan
Trends in Biotechnology 2025
Effects of feruloyl-CoA 6′-hydroxylase 1 overexpression on lignin and cell wall characteristics in transgenic hybrid aspen
Naning Wang, Masatsugu Takada, Shingo Sakamoto, Ruben Vanholme, Geert Goeminne, Hoon Kim, Soichiro Nagano, Naoki Takata, Naofumi Kamimura, Mikiko Uesugi, Akiko Izumi-Nakagawa, Eiji Masai, Nobutaka Mitsuda, Wout Boerjan, John Ralph, Shinya Kajita
Front. Plant Sci. 2025
Extracellular vesicles of Norway spruce contain precursors and enzymes for lignin formation and salicylic acid
Santeri Kankaanpää, Enni Väisänen, Geert Goeminne, Rabah Soliymani, Sandrien Desmet, Anatoliy Samoylenko, Seppo Vainio, Gunnar Wingsle, Wout Boerjan, Ruben Vanholme, Anna Kärkönen
Plant Physiology 2024
Metabolite-based inter-kingdom communication controls intestinal tissue recovery following chemotherapeutic injury
Christopher J. Anderson, Laura Boeckaerts, Priscilla Chin, Javier Burgoa Cardas, Wei Xie, Amanda Gonçalves, Gillian Blancke, Sam Benson, Sebastian Rogatti, Mariska S. Simpson, Anna Davey, Sze Men Choi, Sandrien Desmet, Summer D. Bushman, Geert Goeminne, Peter Vandenabeele, Mahesh S. Desai, Lars Vereecke, Kodi S. Ravichandran
Cell Host & Microbe 2024
Rerouting of the lignin biosynthetic pathway by inhibition of cytosolic shikimate recycling in transgenic hybrid aspen
Hu S, Kamimura N, Sakamoto S, Nagano S, Takata N, Liu S, Goeminne G, Vanholme R, Uesugi M, Yamamoto M, Hishiyama S, Kim H, Boerjan W, Ralph J, Masai E, Mitsuda N, Kajita S.
Plant J. 2022 Apr;110(2):358-376.
CRISPR-Cas9 editing of CAFFEOYL SHIKIMATE ESTERASE 1 and 2 shows their importance and partial redundancy in lignification in Populus tremula × P. alba
de Vries L, Brouckaert M, Chanoca A, Kim H, Regner MR, Timokhin VI, Sun Y, De Meester B, Van Doorsselaere J, Goeminne G, Chiang VL, Wang JP, Ralph J, Morreel K, Vanholme R, Boerjan W.
Plant Biotechnol J. 2021 Nov;19(11):2221-2234.
Maize specialized metabolome networks reveal organ-preferential mixed glycosides
Desmet S, Saeys Y, Verstaen K, Dauwe R, Kim H, Niculaes C, Fukushima A, Goeminne G, Vanholme R, Ralph J, Boerjan W, Morreel K.
Comput Struct Biotechnol J. 2021 Jan 26;19:1127-1144.
Different Routes for Conifer- and Sinapaldehyde and Higher Saccharification upon Deficiency in the Dehydrogenase CAD1
Van Acker R, Déjardin A, Desmet S, Hoengenaert L, Vanholme R, Morreel K, Laurans F, Kim H, Santoro N, Foster C, Goeminne G, Légée F, Lapierre C, Pilate G, Ralph J, Boerjan W.
Plant Physiol. 2017 Nov;175(3):1018-1039.